GEM is an Italian manufacturer and distributor of medical devices, founded in 1994 with a business culture primarily based on research, development, production and marketing of innovative medical devices. In 1995 GEM launched Glubran, a synthetic surgical glue. Afterwards, GEM started manufacturing Glubran 2, the second generation of the product with a new formula allowing also endovascular uses. In 1998 both products obtained CE certification for internal use. At present, Glubran 2 is worldwide appreciated by users for its variety and diversity of uses. In addition, GEM has designed and manufactured several Glubran 2 application devices, facilitating and enhancing its uses. Nowadays, both Glubran 2 and Glubran Tiss 2, as well as their application devices, are distributed in more than 40 countries worldwide. GEM is a research based company, with a key focus on the development of innovative MDs, playing a critical role in an increasingly sophisticated market.