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Michael J. Davis, PhD

Professor
University of Missouri
University of Missouri School of Medicine
Columbia, MO, United States


Michael J Davis, PhD. Professor of Medical Pharmacology & Physiology, University of Missouri.

I am a senior research scientist employed by Texas A&M University College of Medicine from 1985-2005 and the University of MIssouri School of Medicine from 2005-present. The consistent theme of my research career has been mechanisms underlying vascular mechanotransduction. My laboratory was one of the first to develop isolated vessel methods to study small arterioles and to adapt patch clamp and calcium imaging methods to study ion channels in mechanotransduction by endothelial and vascular smooth muscle cells. In recent years we have pioneered methods to study mechanotransduction in the mouse lymphatic system. My work now focuses on the physiological properties of lymphatic smooth muscle and endothelium and how their dysfunction contributes to lymphedema. Currently, I am funded by the NIH to study the contractile and valve properties of lymphatic vessels in mouse models of human diseases. I also serve as a co-investigator on other NIH projects to contribute my expertise in assessing valve function in mouse models of human lymphatic disease, including lymphedema distichiasis, Cantú Syndrome and Ras-pathway mutations.

Disclosure(s):

The forementioned Program Planner, Faculty, Author, Moderator, or Speaker, has declared for this educational activity, having no relevant financial relationship(s) with ineligible companies to disclose.

Presentation(s):

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